The Hospital serves long and short-term travellers, immigrants and refugee populations. It also provides the clinical infectious disease service for University College London Hospitals NHS Foundation Trust and houses the National Travel Health Network and Centre and the Find and Treat service. Services include infection control at UCLH, infectious and tropical diseases, National Travel Health Network and Centre (NaTHNaC) and TB (tuberculosis) services.
Patients at the hospital are referred from general practitioners and other hospitals. It also has an emergency self-referral service for certain conditions.