Making a difference for patients at UCLH

Home Support our funds Clinical speciality funds Dementia

Dementia

The dementia fund provides support groups for patients suffering with the disease

The  Dementia Research Centre

The Dementia Research Centre (DRC) at University College London, is a nationally and internationally recognised centre for patient-centred clinical research in the dementias and the leading UK centre undertaking clinical trials in the dementias. As well as undertaking a wide range of industry trials, the team also run more advanced and invasive studies capitalising on a purpose built dementia clinical trials unit at Queen Square.

The DRC is closely aligned to the Cognitive Disorders Clinics at the National Hospital for Neurology, from where the majority of patients entering our research studies are recruited. The team are committed to closely aligning the research and clinical pathways and also provide dedicated support for patients with unusual dementias, through Rare Dementia Support. Their mission -  to improve the lives of patients with dementia, at risk of dementia, and those living with and caring for patients with dementia. 

The kind of research projects we fund

The research programme is very varied both in the types of dementia the team studies, and the tools they use:

  • The team research “typical” (memory led) Alzheimer’s disease, posterior cortical atrophy (the visual variant of Alzheimer’s disease) and frontotemporal dementia (where speech or behaviour are the dominant problems).  They lead research programmes in familial (i.e. inherited) Alzheimer’s disease and frontotemporal dementia and are also leading a major study to detect pre-symptomatic Alzheimer’s disease in the general population, with the aim of determining which individuals might best enter new clinical trials to prevent he onset of cognitive decline.  
  • The centre is equiped with state of the art diagnostic tools including magnetic resonance imaging (MRI) and positron emission tomography (PET) scanning, and cerebrospinal fluid and blood based biomarkers to understand how the brain goes wrong in these conditions; to distinguish patients with different forms of dementia from one another; to detect disease very early; and to predict and quantify the rate of progression – information that is vital for clinical trials.

By donating  to the fund you will support the departments on-going clinical studies – particularly those using brain imaging, and the patient support groups.